Gehonoreerde projecten wetenschappelijk Fonds Willy Gepts

2023

  • Improving human biphasic oocyte in vitro maturation through optimizing culture oxygen tension- Anckaert Ellen
  • Investigation into coronary hemodynamics and physiology using pulsatile flow- Argacha Jean-FranƧois
  • Engineered male and female reproductive tissues and cells: leveraging gonadal organoids and stem cell-derived germ cells for the study of fertility disruptors - Baert Yoni
  • Effect of individualized nutritional therapy on follicular fluid composition, granulosa cell transcriptome, embryo quality and endometrium in obese patients undergoing art treatment ā€“the nutrifoll study - Blockeel Christophe 
  • Investigating the Spatiotemporal Effects of Radio(nuclide)therapy on Prostate cancer using intravital two-photon microscopy (SERPent) - Debacker Jens
  • To validate circulating biomarkers identifying loss of intrinsic capacity and frailty status in community dwelling elderly - Brussels Study on the early predictors of frailty (Butterfly-project) - Debain Aziz
  • INVISIBLE: Investigation and inhibition of Epstein-Barr Virus immune evasion by BILF1-modulating nanobodies - DeGroof Timo
  • A phase I study to assess the safety and feasibility of adjuvant treatment with a KRAS mutation-specific synthetic long peptide vaccine in combination with nivolumab in patients with non-metastatic PDAC (KRAS-vac1) - deHaar-Holleman Amy
  • Clinical optimisation of pre-implantation genetic testing in the IVF lab - DeMunck Neelke
  • Nanoparticle encapsulated self-amplifying RNA-based vaccination as a novel therapeutic approach against HIV - denRoover Sabine PhD
  • Development of endotype- and phototype specific human 3D skin models for improved treatment modalities of atopic dermatitis - DeVriese Shauni
  • The relation between the gut microbiota composition, chronic pain and spinal cord stimulation [TRACT] - Goudman Lisa
  • Development of an unbiased NanoCAR selection approach for the treatment of multiple myeloma - Hanssens Heleen PhD
  • Unravelling the pathophysiology of unclassifiable inflammatory skin diseases: insight from transcriptomic analysis - Huyghen Lisa
  • Establishing prognostic biomarker signatures based on gene expression patterns and multiplex immunofluorescence staining patterns in AJCC stage I/II melanoma patients - Kessels Jolien
  • At higher risk for pre-eclampsia following assisted reproduction: in search for biomarkers in the preconceptional endometrium of PCOS patients and oocyte recipients - Mackens Shari 
  • Fluorescent Nanobodies: a tool to leverage surgical cancer management to a maximum patient advantage - Mateusiak Lukasz PhD
  • Exercise therapy for osteoarthritis pain: how does it work? (KOA PAIN trial) - Puts Sofie PhD
  • Investigation of adipose tissue-derived exosomal miRNAs in the development and resolution of non-alcoholic steatohepatitis - Rodrigues Robim Marcelino
  • Preclinical development of a human relevant in vitro model to study HGD mRNA therapy in alkaptonuria - Rombaut Matthias PhD
  • Set-up of an in vitro model to predict cholestatic drug induced liver injury - Sanz Serrano Julen
  • Chemogenetic modulation of microglia in a mouse model of drug-resistant limbic epilepsy- Smolders Ilse
  • Comparing primary hysteroscopic resection to medical management of early miscarriage: a randomized controlled trial - Soares Michelle 
  • Pannexin1 channels as pharmacological targets for the treatment of non-alcoholic steatohepatitis - Tabernilla AndrĆ©s
  • Correlation of patient outcome with the neoantigen repertoire, the composition of the tumor microenvironment and neoantigen reactivity of T cells in cerebrospinal fluid for recurrent glioblastoma patients treated with intracerebral immune checkpoint blockade and autologous myeloid dendritic cells - Tuyaerts Sandra
  • DEliriuM In Stroke (DE-MIST): the link between post-stroke delirium and post-stroke cognitive impairment - Vandervorst Fenne
  • The role of ctDNA in the detection of molecular residual disease in early and locally advanced stage non-small cell lung cancer - Vekens Karolien
  • Optimization of in vitro follicle culture methods in mouse to improve developmental competence and offspring health - Zisiadi Aimilia

2022

  • Implementing RoteaTM to advance dendritic cell therapy - Breckpot Karine
  • High frequency rTMS for the treatment of neuropathic pain in diabetic patients - Cordenier Ann
  • The role of mTOR signalling in the effects of transcranial direct current stimulation on plasticity and behavioural dysfunction in a mouse model for autism spectrum disorder ā€“ De Bundel Dimitri
  • FixAKUre: High-throughput screening of a chemical compound library with the aim to identify restabilizing compounds for homogentisate 1,2-dioxygenase enzyme variants in the context of rare disease alkaptonuria ā€“ De Kock Joery
  • MACBETh: Uncovering the role of MACrophages in BETa cell (re)generation - DeLeu Nico
  • Combined cognitive-motor telerehabilitation: a novel strategy to achieve remyelination and neuroprotection in multiple sclerosis? ā€“ Dā€™Haeseleer Miguel
  • FLT3L expressing HSV-1 derived oncolytic virus plus myeloid dendritic cells as a combination therapy for advanced melanoma patients refractory to immune checkpoint blockade - Geeraerts Xenia
  • The therapeutic target system xc- in pancreatic cancer: focus on immune cells and the repurposing of sulfasalazine - Janssen Pauline, PhD student
  • Ketone Esters in Autosomal Dominant Polycystic Kidney Disease: Can Ketone esters shrink the cysts? Feasibility and Proof of Concept study - Janssens Peter
  • Evaluating the clinical impact of SyntOFF, a novel compound targeting pro-tumoral exosomes in Multiple Myeloma - Menu Eline
  • Development of an advance care planning website for people with dementia and their family carers - Monnet Fanny, PhD student
  • SPARTAN: SLIT-ROBO Library screening for PAncReaTic cANcer - Rooman Ilse
  • Dissecting the role of Neurogenin 3 in delta cell development and beta cell regeneration - Staels Willem
  • A randomized comparative evaluation of Superior Rectal Arterial Embolization in hemorrhoidal disease - Surmont Magali
  • Pannexin1 channels as pharmacological targets for the treatment of non-alcoholic steatohepatitis - Tabernilla Andres

2021

  • Harnessing the potential of the THP-chelator: moving toward the development of a clinical-grade kit for immuno-PET imaging - Bridoux Jessica
  • Determination of neurofilament light chain in the interstitial fluid of the mouse brain, a novel biomarker for epilepsy disease progression? - Custers Marie-Laure
  • Pulmonary Hypertension in Extremely Preterm Infants - A Prospective Cohort Study - DeBisschop Barbara
  • Personalized mRNA cancer therapy: Validation and Vaccination - DeMey Wout
  • From the belly to the brain - a call between Basil and Bacillus - Demuyser Thomas
  • DEliriuM In Stroke (DE-MIST): Towards a better understanding of post-stroke delirium (PSD) Is impaired cerebral autoregulation a key driver of PSD? - DeRaedt Sylvie
  • Bone marrow niche ā€“ lung cancer crosstalk: gossip or fatal choice of words? - Goyvaerts Cleo
  • Development of a nanoCAR-T cell approach for the treatment of multiple myeloma - Hanssens Heleen
  • High throughput micro-encapsulation strategies for beta cell therapy - Hellemans Karine
  • Development and validation of an application for segmental measures and body weight and height measurements in children - Huysentruyt Koen
  • Evaluation of the wash-out & wash-in period in patients treated with spinal cord stimulation. - Moens Maarten
  • Transcriptomics to facilitate diagnosis and stratification for children with rheumatic symptoms - Ogunjimi Benson
  • Quantifying the impact of Covid-19 on non-Covid19 hospital care (Quantico) - Pien Karen
  • Appropriateness of end-of-life care in children with serious illness: A population-level study using administrative data - Piette Veerle
  • In-vitro spermatogenesis through testis modelling: Toward the generation of testicular organoids - Richer Guilaume
  • Structural variant detection in clinical practice ā€“ an infertility case study - Stouffs Katrien
  • Expression of B7-H3 as a prognostic and predictive factor for recurrent glioblastoma - Tijtgat Jens
  • ā€œATTACKā€: Next-generation T-cell immunotherapy directed against lymphoid malignancies - Tipanee Jaitip
  • Family carers of people with a serious chronic illness: their perspectives and experiences about advance care planning and end-of-life care. - Vandenbogaerde Isabel
  • Can food additives cause liver damage? - Vinken Mathieu
  • Unraveling the molecular etiology of lysosomal storage diseases - VoNgoc Doan

2020

2019

  • Analyzing T Cell receptor usage in tumor sample and organ that is affected by immunotoxicity in cancer patients receiving immune checkpoint blockade - Aspeslagh Sabine
  • Do time-related trajectories of muscle alterations predict gait recovery in stroke patients in the acute hospital setting? Two multicentre cohort studies. - BeckwĆ©e David
  • Follow-up of pubertal development and fertility in boys who underwent testicular tissue biopsy for fertility preservation. - Braye Aude 
  • Hitting multiple myeloma cells from multiple angles using Galsome vaccination and immune checkpoint inhibition. - Breckpot Karine
  • Immuno-PET imaging using the human anti PD-L1 Nanobody: development of radiolabelling techniques - Bridoux Jessica 
  • Genetics and neuropathology of MCD ā€“ integrating complementary approaches for a better understanding of cortical malformations and normal brain development - Brock Stefanie
  • Riglo ā€“ Redefining Neuromuscular Monitoring - Carvalho Hugo
  • The role of the de novo DNA methyltransferase 3B (DNMT3B) in multiple myeloma cell survival and drug resistance: paving the way to personalized treatment? - De Bruyne Elke
  • Evaluation of monodisperse microparticles for advanced cell therapy - Hellemans Karine
  • Continuous glucose monitoring to predict impending dysglycemia and clinical onset in asymptomatic type 1 diabetes - Keymeulen Bart
  • Optimization of an organotypic 3D-skin equivalent - Kortekaas Inge
  • Analyzing toxicity (local and systemic), osseointegration and brain magnetic resonance imaging of different materials for cranioplasty: a study in New-Zealand white rabbits. - Las David
  • Investigating the role of myeloid cell subpopulations in immune evasion and dormancy in multiple myeloma. - Maes Ken
  • Development of nanobodies directed against xCT (Slc7a11) as therapeutic, diagnostic and research tools - Massie Ann
  • Mitochondrial DNA variants in ART and early human development - Mertens Joke 
  • Palliative care for people with dementia - Miranda Rose 
  • Role of the left atrium anatomy and function for the prediction of atrial fibrillation recurrence after cryoballoon ablation: additional value of 3D echocardiography and speckle tracking - Motoc Andreea
  • The role of Heat Shock Protein 27 in T-cell Senescence - Njemini Rose
  • Do oocytes from women with unexplained infertility more frequently carry potentially harmful mtDNA variants than oocytes of fertile women? - Spits Claudia
  • Characterising and preventing epileptic discharges in an Alzheimer disease model to improve cognitive outcome. ā€“ Vande Vyver Maxime
  • The use of PDGFRb as biomarker to identify Type 2 diabetes mellitus patients with mild fibrosis. ā€“ van Grunsven Leo
  • The Primus trial:effect of PRe-operative Inspiratory MUScle training on post-operative pulmonary recovery and complications after cardiac surgery. - Verdaet Dirk
  • Are connexins, pannexins and their (hemi)channels novel biomarkers and pharmacological targets in the prognosis and therapy of liver cancer? - Vinken Mathieu
  • NanoTAT: Development of novel radiopharmaceuticals for targeted alpha therapy of cancer. - Xavier Catarina

2018

  • Accelerated deep TMS in the elderly depressed: a brain imaging approach - Baeken Chris
  • Self-perceived fatigue in childhood cancer survivors, in relation to body composition, physical outcomes and inflammatory parameters - Ceulemans Anne
  • Initiation of ovarian stimulation with recombinant-human FSH (BemfolaĀ®) in the late follicular phase, a randomised controlled pilot study - De Rijdt Sylvie
  • mRNA therapy for experimental beta(-like) cell transplantation - De Leu Nico
  • A population-level evaluation of the quality of end-of-life care - De Schreye Robrecht
  • DIabetes Mellitus patients undergoing SUrgery on foot Ulcers: what is their Metabolic profile and are nutritional goals met? - De Waele Elisabeth
  • Augmented Reality 3D representation of ultrasound medical images for use in interventional procedures - Duerinck Johnny
  • Exploring coagulation activation during hemodialysis and clinical validation of a hemodialysis strategy free of systemic anticoagulation - Francois Karlien
  • The development and evaluation of an advance care planning programme in nursing homes in Flanders: a cluster randomised controlled trial and mixed-methods process evaluation - Gilissen Joni
  • USP13 mediated inhibition of cCBL, a novel co-target for EGFR targeted therapies in EGFR mutant non-small cell lung cancer - Giron Philippe
  • Turn back the TIMe of the lung Tumor /nfiltrating Myeloid cells - Goyvaerts Cleo
  • De-resuscitation phase after fluid resuscitation (DARE) during septic shock in patients not transgressing spontaneously to flow phase: Removal of extravascular fluid with continuous renal replacement therapy using hypertonic solutions: Fact or Fiction? - Jacobs Rita
  • Establishment of a 3D-skin culture model to study the therapeutic effect of an herbal formulation on atopic dermatitis-like or psoriasis-like features - Kortekaas Inge
  • Translational CD20 nanobody theranosis: diagnostic imaging and targeted radionuclide therapy of Non-Hodgkin Lymphoma with anti-CD20 nanobody in a humanized mouse model - Krasniqi Ahmet
  • Reducing sleep onset latency with virtual reality in patients suffering from diabetic polyneuropathy. RESOLVE - Moens Maarten
  • Treatment of PREPL deficiency with trimethoprim - Regal Luc
  • The influence of different thyroid autoantibodies on thyroid function and pregnancy outcome after assisted reproductive technology - Unuane David
  • Impact of non-HLA susceptibility alleles on the various asymptomatic stages of type 1 diabetes - Van de Casteele Marc
  • ChIP-NIPT: a novel approach to enrich the foetal fraction in non-invasive prenatal testing to reliably detect (sub)chromosomal copy number variations - Van Dooren Sonia
  • Influence of Assisted Autogenic Drainage and Assisted Autogenic Drainage combined with bouncing on gastro-oesophageal reflux in infants under the age of one year. Van Ginderdeuren Filip

2017

2016

  • Mutations in HRD genes as predictive biomarkers for the effectiveness of neoadjuvant carboplatinum in the and postoperative irradiation in triple negative early breast cancer patients - Fontaine Christel
  • Use of high throughput whole-genome sequencing (WGS) in the typing and epidemiologic surveillance of Bordetella pertussis - Pierard Denis
  • The search for the origin of chromosomal abnormalities in human preimplantation embryos - Sermon Karen
  • Study of mitochondrial DNA changes in placental samples of spontaneous and IVF conceptions - Spits Claudia
  • Immune checkpoint modulation in multiple myeloma: can iNKT cells be targeted? - Favreau MĆ©rĆ©dis
  • Intravital imaging of tumor targeting with nanobodies - Hernot Sophie
  • Evaluation of 68Ga-NOTA-Anti-HER2 Nanobody uptake in brain metastasis of breast carcinoma patients using PET/CT scan - Keyaerts Marleen
  • A preclinical study to investigate the potential of S100A9 inhibitors in the treatment of Multiple Myeloma - Vanderkerken Karin
  • Development of a GMP compliant and fully automated 18F-radiochemistry unit for clinical translation of 18F-nanobodies - Vaneycken Ilse
  • Hair Cortisol Concentration as a Biomarker for Parental Stress. A study of the correlation between the chronic cortisol response in parents and pathology in their children, and its possible mediation by attachment status of the child - Campforts Edward
  • N-acetylcysteine for the treatment of cannabis dependence: working mechanisms - Crunelle Cleo
  • OptiBIRTH: Improving the organisation of maternal health service delivery, and optimising childbirth, by increasing vaginal birth after caesarean section (VBAC) through enhanced women-centred care ā€“ health economic analysis - Fobelets Maaike
  • Phase I clinical trial on systemic PD-1 blockade in combination with intra-tumoral CTLA-4 immune-checkpoint blockade following the resection of recurrent glioblastoma - Neyns Bart
  • The systematic early integration of palliative care into multidisciplinary oncology care in the hospital setting (IPAC), a randomized controlled trial - Vanbutsele Gaelle
  • The impact of maternal decidualization on human blastocyst development - Aberkane Asma
  • Significance of cytokines as markers for oocyte quality, embryo development and clinical pregnancy in ART patients - Anckaert Ellen
  • Oxygen a key regulator for implantation and trophoblast differentiation - Vandevelde Hilde
  • CAMEL-KIT: Single-step labeling of single domain antibody fragments with 68Ga for PET imaging - Baudhuin Henri
  • Translational CD20 nanobody theranosis: diagnostic imaging and targeted radionuclide therapy of Non-Hodgkin Lymphoma with anti-CD20 nanobodies in a humanised mouse model - Devoogdt Nick
  • Targeting brain tumors and metastases using therapeutic radiolabeled Nanobodies - D'Huyvetter Matthias
  • On-line CAre for secondary stroke Prevention (OCAPi) - Brouns Raf
  • Using a Humanoid Robot to Provide Pain Neuroscience Education to Children with Leukemia Undergoing Painful Procedures: a Monocentric Pilot Study - Ickmans Kelly
  • Development and evaluation of a computerized clinical decision support system for drug allergy checking - Legat Laura
  • Complexity and multidisciplinary approach to fetal pathology: can we improve diagnostics and enhance geno-/phenotype correlation? - Van Berkel Kim
  • Reprogramming of umbilical cord-derived mesenchymal stem cells towards hepatocyte-like cells by repeated expression of hepatic transcription factors - Buyl Karolien
  • Biomarker discovery and advanced monitoring of new cell-based therapies for hereditary tyrosinemia type 1 - De Kock Joery
  • Hemichannels as novel pharmacological targets and biomarkers of cholestasis - Vinken Mathieu
  • Klinefelter related infertility: getting to know causes - Van Saen Dorien
  • The effect of meiotic gene mutations on human reproduction - Verpoest Willem
  • Role of natural killer cells in HIV post-treatment control - Aerts Joeri

2015

  • The development of a 3D culture system for human in-vitro spermatogenesis - Baert Yoni
  • Minimal residual disease quantification using high-throughput IGH sequencing in multiple myeloma patients who received dendritic cell based immunotherapy - Bakkus Marleen
  • PET-imaging of tumour supporting macrophages in the tumour microenvironment using 18FNanobodies - Blykers Anneleen
  • Gene editing of a dominant pathogenic allele in human induced pluripotent stem cells (iPS) derived from myotonic dystrophy (DM1) patients - Dastidar Sumativa
  • Chemogenetic modulation of astrocytes in temporal lobe epilepsy and its comorbidities - De Bundel Dimitri
  • Improved targeted therapies in non-small cell lung cancer: an unbiased approach to increase treatment efficacy - De GrĆØve Jacques  
  • RNA therapy for beta cell regeneration and transplantation - De Leu Nico
  • The role of myeloid-derived suppressor cells in multiple myeloma drug resistance - De Veirman Kim
  • Characterisation of copy number variations posing a high safety risk upon transplantation of human pluripotent stem cell-derived cell populations - Geens Mieke
  • Investigating the genetic basis of lysosomal storage diseases by implementation of massive parallel sequencing - Gheldof Alexander
  • Development of polymer microparticles for beta cell therapy - Hellemans Karine
  • Beta cell generation by embryonic stem cell-derived implants in type 1 diabetes - Hilbrands Robert
  • A phase I study on the safety and immune-modulatory effect of intra-lesional administration of mRNA encoding dendritic cell activating proteins in patients with early breast cancer - Lamote Jan
  • Development and investigation of the feasibility and effects of a specific motion interactive game training the tibialis anterior muscle in children with cerebral palsy - Laumen Armand
  • Development of nanobody-based probes for pancreatic beta cell mass imaging - Massa Sam
  • Improving 3D-navigation for cervical dorsal root ganglion stimulation - Moens Maarten
  • Study of the pathogenic mechanisms of mutations in the SERPINC1 gene responsible for inherited antithrombin deficiency - Orlando Christelle
  • Establishing the role of autophagy, and its link with inflammation and cell death, in rodent models of temporal lobe epilepsy - Smolders Ilse
  • A 3D tissue culture model for screening of anti-fibrotic compounds - Van Grunsven Leo
  • Stratified phase IB clinical trial in patients with advanced melanoma and non-small cell lung cancer: investigating the combination of a natural dendritic cell vaccine plus an anti-PD-1 monoclonal antibody as first-line immunotherapy - Wilgenhof Sofie
  • High-resolution 3D imaging of microcalcifications using micro-CT - Willekens Inneke

2014

  • Psychosocial support during pregnancy in vulnerable women. Randomised controlled trial measuring the effects on the routine antenatal care trajectory and perceived pscyhosocial stress - Beeckman Katrien
  • Beta cell protective and antidiabetic effects of aspalathin and a phenylpyruvic acid glucoside from rooibos ā€“ a preclinical study - Bouwens Luc
  • Exploring the continuum of functional decline across cognitively healthy ageing, Mild Cognitive Impairment and Alzheimer's disease, using The Brussels Integrated Activities of Daily Living questionnaire - Cornelis Elise
  • Analysis of the impact of tofacitinib on keratinocyte differentiation and immune function - Gutermuth Jan
  • Adaptive clinical trial program for combinatorial immunotherapy targeting cancer-testis antigens in patients with advanced colorectal cancer - Jansen Yanina
  • Towards the identification and characterization of novel gene defects in patients with a mitochondrial disease - Jonckheere An
  • Assesment of the added value of molecular karyotyping compared to standard karyotyping in couples with recurrent miscarriages - Keymolen Kathelijn
  • Development of a transposon-based stem cell-gene therapy for Duchenne muscular dystrophy - Loperfido Mariana
  • Use of whole genome next-generation sequencing (WG-NGS) in the typing and outbreak investigation of Shiga toxin-producing Escherichia coli (STEC) - Pierard Denis
  • Care and Place of Care at the End of Life: International Perspectives - Pivodic Lara
  • Effect of vitamin D deficiency on endometrial receptivity and oocyte quality in infertile women undergoing in vitro fertilization - Polyzos Nikolaos
  • Circulating nucleic acids as high-sensitivity biomarkers for occult beta cell destruction in type 1 diabetes - Roels Sarah
  • Genetic predisposition of ovarian hyperstimulation syndrome - dos Santos Ribeiro Samuel
  • Evaluation of the performance of an adapted endotracheal tube (i.e. double-cuffed with providing continuous positive pressure in the intercuff space) on inflow of oropharyngeal secretions in mechanically ventilated patients. An observational study - Spapen Herbert
  • Do mitochondrial DNA mutations play a role in the outcome of assisted reproduction technologies? - Spits Claudia
  • Fertility preservation in boys facing stem cell loss: translation to a clinical application - Tournaye Herman
  • The genetic complexity of Brugada syndrome: a multiple hit disease model? - Van Dooren Sonia
  • Investigation of trophectoderm regulators playing a role in human embryo implantation - Vandevelde Hilde

2013

  • Assessment of arterial flow in distal foot arteries by current ultrasound technique: to determining its role in angiosome-guided revascularization in diabetic foot patients - Aerden Dimitri
  • Testing the epigenetic safety of IVM in children born at UZ Brussel and risk assessment of IVM using a mouse model - Anckaert Ellen
  • Clonal complexity in childhood acute lymphoblastic leukemia: biological significance and clinical impact - Bakkus Marleen
  • Long-term health outcome of young adults conceived by IntraCytoplasmic Sperm Injection (ICSI) - Belva Florence
  • Evaluation of the role of human mesenchymal stem cells in experimental islet transplantation - Heimberg Harry
  • Towards improved genetic diagnosis for hereditary breast and ovarian cancer - De GrĆØve Jacques
  • Exploration of translational potential of human skin-derived precursor cells and their in vitro generated hepatic derivatives in experimental liver disease models - De Kock Joery
  • Arginase as a predictive biomarker and molecular target in chemo/radiotherapy of metastatic colorectal cancer - De Ridder Mark
  • Study on the T-cell immune response in frequently HIV-1 exposed but seronegative individuals - Demanet Christian
  • In vivo Characterization of Atherosclerotic Plaques with 18F-Labeled Nanobodies - Droogmans Steven
  • Non-invasive mapping of tumor hypoxia for Biologically Modulated Radiotherapy in patients with locally advanced head-and-neck cancer - Everaert Hendrik
  • METHODS/MODELS FOR IN VIVO STIMULATION OF BETA CELL REPLICATION - Hellemans Karine
  • Intra-operative NIR-fluorescence image-guidance during breast cancer surgery - Lahoutte Tony
  • Malformations of cortical development: identification of novel genes and their function - Jansen Anna
  • Validation of a novel combined hyperinsulinemic euglycemic / hyperglycaemic clamp technique to measure simultaneously insulin secretion and resistance in a single test and comparison with the mixed meal tolerance test - Keymeulen Bart
  • Therapeutic vaccination against HIV by direct administration of mRNA encoding HIV antigens and activation signals - Lacor Patrick
  • A phase I study on the feasibility and safety of mRNA immunotherapy in combination with RFA in patients with hepatocellular carcinoma - Reynaert Hendrik
  • Investigation of implantation regulators in the human embryo - Vandevelde Hilde
  • From an invasive to a non-invasive test for pregnancy outcome - Vercammen Martine
  • GNAS 1 autoantibodies as new marker for beta cell-directed autoimmunity in type 1 diabetes - Verhaegen Katrijn
  • Proinsulin/C-peptide ratio as a marker of functional beta cell mass in (pre) type 1 diabetes and in beta cell therapy - Weets Ilse

2012

  • Prospective Randomized Control Trial on Cumulus Cell gene expression based: Pregnancy Prediction to improve the live birth rate in ICSI patients - Adriaenssens Tom
  • The neurobiological effects of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) on alcohol craving in alcohol dependent patients - Baeken Chris
  • Pre-hospital Stroke Study at the Universitair ziekenhuis Brussel (PreSSUB) - Brouns Raf
  • Cerebral axonal and astrocytic energy metabolism and glutamate levels in multiple sclerosis - Cambron Melissa
  • Respiration-synchronized radiation of non-small cell lung cancer from the patient's point of view - Collen Christine
  • Development and evaluation of a computerised clinical decision support system for dosing guidance in patients with renal insufficiency - Cornu Pieter
  • Spermatogonial stem cell retrieval and cryopreservation in young boys with Klinefelter syndrome: an attempt to preserve their future fertility - De Schepper Jean
  • Therapeutic mRNA based immunotherapy of hr-HPV positive cervical intraepithelial neoplasia (CIN grade 2-3) - De Sutter Philippe
  • Beta Cell Therapy in Type 1 Diabetes - Keymeulen Bart
  • Development of a bead-based immunoassay for PPP1R1A as novel biomarker of beta cell destruction in vivo - Martens Geert
  • Neural influence in the resolution of type 2 diabetes mellitus after Roux-en-Y gastric bypass in patients with morbid obesity - Muylaert Caroline
  • Unraveling of genetic factors involved in male fertility - Stouffs Katrien
  • Fertility preservation in boys facing stem cell loss: translation to a clinical application - Tournaye Herman
  • Knee osteoarthritis exercise therapy (KNOET) - Vaes Peter
  • Development of innovative therapies to prevent or treat damages of the glomerular filtration barrier by mTOR antagonists and inhibitors of VEGF signaling - Van Beneden Katrien
  • Unraveling the molecular genetic pathways of Brugada syndrome by cardiomics research - Van Dooren Sonia
  • The immunology of implantation: the role of uterine dendritic cells - Vandevelde Hilde
  • Connexin hemichannels as drug targets in acute liver failure: a combined in vitro-in vivo study - Vinken Mathieu

2011

  • Evidencing potential mechanisms involved in imprinting disorders after human Assisted Reproductive Technology - Anckaert Ellen
  • The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients - Bautmans Ivan
  • Study of the intestinal microbiota in children with crohnā€™s disease (cd) and intervention with prebiotics or probiotics - De Greef Elisabeth
  • Preparation of alginate-embedded human islet cell grafts for transplantaion in diabetic patients - Gorus Frans
  • Insulin-like growth factor-based treatment for acute ischemic stroke - Kooijman Ron
  • Prospective comprehensive study of the new medical treatment options for patients with advanced melanoma - Neyns Bart
  • Impact of bilateral ganglion stellatum blockade on complex fractionated atrial electrograms during hybrid thoracoscopic ablation of atrial fibrillation - Sarkozy Andrea
  • Gene therapy for hemophylia "A" using "immune stealth" nanoparticles: preclinical validation in anticipation of phase I clinical trials in patients with severe hemophilia "A" - Vandendriessche Thierry
  • Prehospital stroke study at the Universitair Ziekenhuis Brussel (PreSSUB) - Brouns Raf
  • Biologically modulated radiotherapy for locally advanced pancreatic cancer on the VERO-SBRT system - Christian Nicolas
  • Validation of integrated backscatter echocardiography as a new tool for quantifying the degree of aortic valve calcification in patients - Cosyns Bernard
  • 13C gastric emptying breath tests in children: comparison of non-dispersive infrared spectrometry and isotope ratio-mass spectrometry tests - Hauser Bruno
  • Randomized phase III trial of preoperative radiotherapy with an integrated simultaneous boost compared to chemoradiotherapy for t3-4 rectal cancer: central pathology review and translational study - Hoorens Anne
  • Impact of the maze procedure in one atrial fibrillation on the sympathetic activity of the heart assessed by 123I-MIBG - La Meir Mark
  • The physical and psychological development of 5-year-old children born after preimplantation genetic diagnosis (PGD) compared to children born after intracytoplasmic sperm injection (ICSI) and natural conception - Nekkebroeck Julie
  • Characterisation of epidermal permeability barrier function in filaggrin deficient humans and mouse models - Roelandt Truus
  • DC VACCINES KNOCK YOUR SOX OFF: Preclinical and clinical studies to investigate the role of SOX2 as a potential target to induce cellular immune responses against myeloma cells - Schots Rik
  • Circulating tumor cells and circulating endothelial cells in operable NSCLC: a study on kinetics and molecular-genetic characteristics - Smets Dirk
  • Pregnancy outcome of ICSI cycles after closed incubation with time-lapse automated embryo evaluation or standard incubation with classical morphological embryo evaluation - Van de Velde Hilde